(R) -5-Oxopyrrolidine-2-carboxylic acid - CAS 4042-36-8

(R) -5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It releases GABA from the cerebral cortex and exhibits anti-anxiety effects in a simple approach-avoidance conflict situation in rats. In clinical pharmacology experiments, it significantly shortens the plasma half-life of ethanol during acute intoxication.

Endogenous Metabolite

Metabolism

3998

0.9988

C5H7NO3

129.11

OC(=O)[C@H]1CCC(=O)N1

-20°C

Ice Packs

Natural Product