(R) -9b - CAS 1655527-68-6

(R) -9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer activity. It selectively targets ACK1 but also inhibits kinases in the JAK family, specifically JAK2 and Tyk2. (R) -9b is used in research related to hormone-regulated cancers, such as prostate cancer and breast cancer.

JAK, ACK1

Stem Cells, Angiogenesis, Chromatin/Epigenetic, JAK/STAT signaling, Tyrosine Kinase/Adaptors

1655453

C20H27ClN6O

402.92

N(C1=CC=C(C=C1)N2CCN(C)CC2)C=3N=C(NC[C@H]4CCCO4)C(Cl)=CN3

-20°C

Ice Packs

Small Compound