(R) -Acenocoumarol - CAS 66556-77-2

(R) -Acenocoumarol ((R) -Acenocoumarin; (R) -Nicoumalone) is a short-acting, orally administered anticoagulant that works by inhibiting vitamin K epoxide reductase (vitamin K1 recycling), similar to Warfarin. It demonstrates greater anticoagulant potency in vivo compared to Warfarin. This compound has a single chiral center, resulting in two enantiomeric forms. The (R) -enantiomer has a longer plasma elimination half-life of 6.6 hours, slower plasma clearance of 1.9 L/h, and stronger anticoagulation effects than the (S) -enantiomer.

Vitamin

Metabolism

66477

C19H15NO6

353.33

CC(C[C@H](C1=CC=C(C=C1)[N+]([O-])=O)C2=C(C3=CC=CC=C3OC2=O)O)=O

-20°C

Ice Packs

Small Compound