(R) -Bambuterol - CAS 788821-30-7

Bambuterol is a prodrug of β2-agonist commonly used for the treatment of asthma and chronic obstructive pulmonary disease (COPD) with the advantage of once daily dosing and favorable side effect profile. Administration of a single-dose of R-bambuterol resulted in dose-dependent reductions in the levels of plasma LDL-C, high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC), apolipoprotein B (ApoB) and apolipoprotein A1 (ApoA1) at Tmax. R-bambuterol can lower the plasma levels of LDL-C, and marginally raise the ratio of ApoA1/ApoB (indicator of HDL-C/LDL-C) with both a single dose and multiple doses. R-bambuterol was more potent in LDL-C lowering than rac-bambutero

Others, Adrenergic Receptor

GPCR/G Protein, Others, Neuroscience

788784

C18H29N3O5

367.44

[C@@H](CNC(C)(C)C)(O)C1=CC(OC(N(C)C)=O)=CC(OC(N(C)C)=O)=C1

-20°C

Ice Packs

Small Compound