(R) -CDK2 degrader 6 - CAS 3083777-50-5

(R) -CDK2 degrader 6 (Compound 7) is the R enantiomer of CDK2 degrader 6. It functions as a selective molecular glue degrader for CDK2, with a DC50 of 27.0 nM within 24 hours. This compound can be utilized in breast cancer research.

Molecular Glues, CDK

Cell Cycle/Checkpoint, PROTAC

3083722

C23H22F5N5O3

511.44

C(F)(F)(F)C12CC(C1)(C2)C=3OC(N[C@@H]4[C@@H](C)N(C4)C5=CC(F)=C(C(F)=C5)[C@@H]6C(=O)NC(=O)CC6)=NN3

-20°C

Ice Packs

PROTAC