(R) - (+) -Docosahexaenyl-1'-Hydroxy-2'-Propylamide - CAS 1282618-08-9

N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Docosahexaenoyl ethanolamide (DHEA) has potential signaling roles in cancer, inflammation, and neurological development and functioning. At least some of DHEA's effects are mediated through cannabinoid (CB) receptors, while some NAEs also act as vanilloid receptor agonists and voltage-gated K+ channel blockers. (R) - (+) -Docosahexaenyl-1'-hydroxy-2'-propylamide is a homolog of DHEA, characterized by the addition of an (R) -α-methyl group at the methylene carbon adjacent to the amide nitrogen. A similar modification of arachidonoyl ethanolamide to produce R-1 methanandamide imparts higher affinity for the CB receptor as well as improved metabolic stability. The physiological actions of this compound have not been evaluated.

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Others

1282618-08-9

C25H39NO2

385.58

C(\CCC(N[C@@H](CO)C)=O)=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC

-20°C

Ice Packs

Small Compound