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(R) -Doxazosin - CAS 70918-17-1
(R) -Doxazosin - CAS 70918-17-1
SKU:MF-0008500-01
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Product Details
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Bioactivity
(R) -Doxazosin ((R) -UK 33274) is an isomer of Doxazosin, a selective oral a1-adrenoceptor agonist. Doxazosin is utilized for systemic antihypertensive and ocular hypotensive purposes. It achieves its antihypertensive effect by selectively blocking postsynaptic a1 receptors, reducing total peripheral resistance without impacting cardiac output. Doxazosin significantly lowers both standing and supine blood pressure.
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Target
Adrenergic Receptor
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Related Pathways
GPCR/G Protein, Neuroscience
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CAS Number
70900
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Molecular Formula
C23H25N5O5
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Molecular Weight
451.48
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SMILES
NC=1C2=C(N=C(N1)N3CCN(C(=O)[C@@H]4OC=5C(OC4)=CC=CC5)CC3)C=C(OC)C(OC)=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound