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(R) - (-) -Gossypol acetic acid - CAS 866541-93-7

(R) - (-) -Gossypol acetic acid - CAS 866541-93-7

SKU:MF-0008351-01

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  • Bioactivity

    (R) - (-) -Gossypol acetic acid (AT101 acetate), the R- (-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL, and Mcl-1 with Ki values of 0.32 μM, 0.48 μM, and 0.18 μM, respectively; it does not inhibit the BIR3 domain or BID. [Phase 2]

  • Target

    Autophagy, Bcl-2 Family

  • Related Pathways

    Apoptosis, Autophagy

  • CAS Number

    866441

  • Purity

    0.995

  • Molecular Formula

    C30H30O8·C2H4O2

  • Molecular Weight

    578.61

  • SMILES

    CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product