(R) -IDO/TDO-IN-1 - CAS 2033173-00-9

(R) -IDO/TDO-IN-1 (compound 25), an indoleamine-2,3-dioxygenase (IDO) inhibitor, demonstrates good pharmacokinetic properties and exerts anti-tumor effects in the MC38 xenograft model. This compound exhibits synergy when combined with the anti-PD-1 monoclonal antibody (SHR-1210) [1].

Others, IDO, Indoleamine 2,3-Dioxygenase (IDO)

Metabolism, Others

2033173-00-9

C25H24FN5

413.49

FC1=C2[C@H](N3C(C2=CC=C1)=CN=C3)C4CCN(CC4)C5=CC=C(C=C5)C6=CN(C)N=C6

-20°C

Ice Packs

Small Compound