(R) -JAK2/STAT3-IN-10a - CAS 2485758-49-2

(R) -JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R) -JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.

Antiviral, Apoptosis

Immunology/Inflammation, Apoptosis

2485707

0.9834

C34H35BrF3N5O2

682.57

C(N)(=O)N1[C@@H](C=2C=3C(N(CC4=CC=C(OCCN5CCCCCC5)C=C4)C2)=CC=C(Br)C3)CC(=N1)C6=CC=C(C(F)(F)F)C=C6

-20°C

Ice Packs

Small Compound