(R) -Lanicemine - CAS 190581-71-6

(R) -Lanicemine ((R) -AZD6765), the less active R-enantiomer of Lanicemine, is a low-trapping NMDA channel blocker. It exhibits a binding affinity (Ki) of 0.56-2.1 μM for the NMDA receptor and shows inhibitory concentrations (IC50s) of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. It has been associated with antidepressant effects [1].

IGluR, Others

Others, Neuroscience, Membrane transporter/Ion channel

190504

C13H14N2

198.26

N[C@H](Cc1ccccn1)c1ccccc1

-20°C

Ice Packs

Small Compound