(R) -MK-8353 - CAS 2748457-30-7

(R) -MK-8353 ((R) -SCH900353) is the R-enantiomer of MK-8353. MK-8353 (SCH900353) is a potent, selective, orally active inhibitor of ERK1 and ERK2, with IC50 values of 23.0 nM and 8.8 nM, respectively.

ERK

MAPK

2748457-30-7

C37H41N9O3S

691.85

N(C(=O)[C@]1(SC)CN(CC(=O)N2CCC(=CC2)C3=CC=C(C=C3)C4=NN(C)C=N4)CC1)C=5C=C6C(=NNC6=CC5)C=7C=CC(OC(C)C)=NC7

-20°C

Ice Packs

Inhibitors & Agonists