(R) -nitro-Blebbistatin - CAS 1217619-62-9

(R) -nitro-Blebbistatin is a more stable form of (+) -blebbistatin , which is the inactive form of (-) -blebbistatin . Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R) -nitro-Blebbistatin has the same stereochemistry as the inactive (+) -blebbistatin enantiomer.

Others, Myosin

Others, Cytoskeletal Signaling

1217548

C17H13N3O4

323.3

O[C@@]12C(N(CC1)C3=CC=CC=C3)=NC=4C(C2=O)=CC=C(N(=O)=O)C4

-20°C

Ice Packs

Small Compound