(R) -Omeprazole (sodium salt) - CAS 161796-77-6

(R) -Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R) -omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S) -enantiomer . (R) -Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM) .

Cytochromes P450, Others

Metabolism, Others

161713

C17H19N3NaO3S

368.41

[NaH].COc1ccc2nc([nH]c2c1)S(=O)Cc1ncc(C)c(OC)c1C

-20°C

Ice Packs

Small Compound