(R, R) -LRRK2-IN-7 - CAS 2307277-92-3

(R, R) -LRRK2-IN-7 is an isomer of LRRK2-IN-7, a potent and selective LRRK2 kinase inhibitor with CNS penetrance. It exhibits an IC50 of 0.9 nM and demonstrates over 1000-fold selectivity compared to other kinases, ion channels, and CYP enzymes.

LRRK2

Autophagy

2307277-92-3

C24H26N6O

414.5

C(#N)[C@]1(C2(C1)CC2)C=3C=C4N(N=CC4=CC3)C=5C=C(N=CN5)N6C[C@H](C(C)(C)O)CC6

-20°C

Ice Packs

Inhibitors & Agonists