(R, S, S) -VH032 - CAS 2230826-33-0

(R, S, S) -VH032 is a ligand for E3 ligase and a VHL/HIF-1α interaction inhibitor utilized in the synthesis of PROTACs, particularly the tau-targeting small molecule PROTAC C004019 [1]. As a VHL ligand, it recruits von Hippel-Lindau (VHL) proteins, facilitating the development of targeted protein degradation therapies.

Ligand for E3 Ligase, Others

PROTAC, Others

2230826-33-0

C22H30N4O3S

430.56

C(NCC1=CC=C(C=C1)C=2SC=NC2C)(=O)[C@@H]3N(C([C@H](C(C)(C)C)N)=O)C[C@@H](O)C3

-20°C

Ice Packs

PROTAC