(R) -SKBG-1 - CAS 2955634-67-8

(R) -SKBG-1 is an inhibitor of the RNA-binding protein NONO, with an EC50 value of 1.5 μM in 22Rv1 cells. (R) -SKBG-1 reduces mRNA and protein expression of the androgen receptor (AR) and its splice variants (AR-FL and AR-V7), inhibits the proliferation of various cancer cells, and affects the transcriptome and proteome of cancer cells.

Androgen Receptor, MicroRNA

Endocrinology/Hormones, Chromatin/Epigenetic

2955559

0.9725

C22H26ClN3O6S

495.98

S(=O)(=O)(N1[C@@H](C(NCC2=CC=C(OC)C=C2)=O)CN(C(CCl)=O)CC1)C3=CC=C(OC)C=C3

-20°C

Ice Packs

Small Compound