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Molfinity

R547 - CAS 741713-40-6

R547 - CAS 741713-40-6

MF-0017005-01

$42.14 USD
$42.14 USD
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Product Details

  • Bioactivity

    R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.

  • Target

    CDK, GSK-3, Apoptosis, PKA

  • Related Pathways

    Cell Cycle/Checkpoint, Stem Cells, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Apoptosis

  • CAS Number

    741667

  • Purity

    0.9984

  • Molecular Formula

    C18H21F2N5O4S

  • Molecular Weight

    441.45

  • SMILES

    COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(CC2)S(C)(=O)=O)nc1N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound