(Rac) -Ibrutinib alkyne - CAS 936563-91-6

(Rac) -Ibrutinib alkyne (Compound 8) is a Btk inhibitor with an IC50 of 0.72 nM. This compound effectively inhibits B cell receptor signaling functions, with an IC50 of 9 nM for calcium flux inhibition in Ramos cells. (Rac) -Ibrutinib alkyne is applicable in research on diseases such as rheumatoid arthritis.

Calcium Channel, BTK

Tyrosine Kinase/Adaptors, Angiogenesis, Metabolism, Membrane transporter/Ion channel

936466

C25H22N6O2

438.48

O=C(C#C)N1CCCC(N2N=C(C=3C=CC(OC=4C=CC=CC4)=CC3)C=5C(=NC=NC52)N)C1

-20°C

Ice Packs

Small Compound