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Molfinity

(Rac) -Indoximod - CAS 26988-72-7

(Rac) -Indoximod - CAS 26988-72-7

MF-0008831

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Product Details

  • Bioactivity

    (Rac) -Indoximod (1-Methyl-DL-tryptophan) is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO) . Combined treatment with IFN-γ and (Rac) -Indoximod significantly suppresses the activity of α-SMA-expressing human cardiac myofibroblasts (hCMs) and promotes apoptosis by up-regulating the genes IRF-1, Fas, and FasL, effectively improving cardiac fibrosis[1].

  • Target

    Others, Apoptosis, Indoleamine 2,3-Dioxygenase (IDO), IDO

  • Related Pathways

    Apoptosis, Others, Metabolism

  • CAS Number

    26909

  • Molecular Formula

    C12H14N2O2

  • Molecular Weight

    218.25

  • SMILES

    Cn1cc(CC(N)C(O)=O)c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound