(Rac) -Ketoconazole - CAS 79156-75-5

(Rac) -Ketoconazole ((Rac) -R 41400) is an orally active antifungal imidazole compound. It inhibits ergosterol synthesis in fungi by targeting the cytochrome P450-dependent enzyme, 14α-sterol demethylase (CYP51), on the fungal cell membrane. This disruption leads to dysfunction of the cell membrane, ultimately hindering fungal growth and proliferation. (Rac) -Ketoconazole is applicable in studying fungal infections.

Antifungal, Cytochromes P450

Microbiology/Virology, Metabolism

79076

C26H28Cl2N4O4

531.43

O=C(N1CCN(C2=CC=C(OCC3OC(OC3)(C4=CC=C(Cl)C=C4Cl)CN5C=NC=C5)C=C2)CC1)C

-20°C

Ice Packs

Small Compound