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Molfinity

(Rac) -Lonafarnib - CAS 193275-86-4

(Rac) -Lonafarnib - CAS 193275-86-4

MF-0008838-01

$1,778.67 USD
$1,778.67 USD
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Product Details

  • Bioactivity

    (Rac) -Lonafarnib (Sch66336 racemate) is the racemic form of the potent, orally active farnesyl transferase (FTase) inhibitor, Lonafarnib. It effectively inhibits H-ras, K-ras, and N-ras with IC50 values of 1.9 nM, 5.2 nM, and 2.8 nM, respectively, and exhibits activities against the hepatitis delta virus (HDV) .

  • Target

    Others, Transferase

  • Related Pathways

    Others, Metabolism

  • CAS Number

    193185

  • Molecular Formula

    C27H31Br2ClN4O2

  • Molecular Weight

    638.82

  • SMILES

    BrC1=C2C(C=3C(CCC2=CC(Cl)=C1)=CC(Br)=CN3)C4CCN(C(CC5CCN(C(N)=O)CC5)=O)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound