(Rac) -P1D-34 - CAS 2957895-04-2

PROTACPIN1degrader-2 (1) is a PROTAC degrader of PIN1. The IC50 values of PROTACPIN1degrader-2 (1) against various cancer cells are as follows: 2248 nM for MV-4-11 cells, 3984 nM for MOLM-13 cells, and 3925 nM for HL-60 cells.

PROTACs

PROTAC

2957895-04-2

C40H59ClN6O9S

835.449

O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)NCCCCCCCCCCCCNC(=O)CCC(=O)NCC(C)(C)CN(C(=O)CCl)C4CCS(=O)(=O)C4)CC1

-20°C

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PROTAC