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(Rac) -PF-4136309 (1341224-83-6 Free base) - CAS 857679-55-1
(Rac) -PF-4136309 (1341224-83-6 Free base) - CAS 857679-55-1
SKU:MF-0008864-01
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Product Details
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Bioactivity
PF-4136309 (INCB8761, PF-04136309) is a highly effective and selective oral CCR2 antagonist with good bioavailability, with an IC50 value of 5.2 nM for human CCR2.
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Target
Others, CCR
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Related Pathways
Others, GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology
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CAS Number
857623
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Molecular Formula
C29H31F3N6O3
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Molecular Weight
568.59
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SMILES
O=C(NC1=NC=C2C=CC(=CC2=C1)C=3C=NN(C3)C)C=4C=CN=C(C4)N5CCN(C)CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound