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Molfinity

(Rac) -SAG - CAS 364590-63-6

(Rac) -SAG - CAS 364590-63-6

MF-0008877-01

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Product Details

  • Bioactivity

    (Rac) -SAG, an isoform of SAG, is a potent Smoothened (Smo) receptor agonist (EC50 = 3 nM; Kd = 59 nM) that activates the Hedgehog signaling pathway and counteracts Cyclopamine's inhibition of Smo [1] [2] [3].

  • Target

    Smo

  • Related Pathways

    Stem Cells

  • CAS Number

    364590-63-6

  • Molecular Formula

    C28H28ClN3OS

  • Molecular Weight

    490.06

  • SMILES

    N(C(=O)C1=C(Cl)C=2C(S1)=CC=CC2)(CC3=CC(=CC=C3)C=4C=CN=CC4)C5CCC(NC)CC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound