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Rademikibart - CAS 2648260-80-2

Rademikibart - CAS 2648260-80-2

SKU:MF-0099961-01

Regular price $223.75 USD
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  • Bioactivity

    Rademikibart (CBP-201) is a humanised monoclonal antibody targeting IL-4Rα (KD = 20.7 pM) that does not interact with IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signalling pathways, TF-1 cell proliferation, and TARC production in PBMCs, making it useful for studying Th2-type inflammatory diseases.

  • Target

    IL Receptor, Interleukin

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    2648260-80-2

  • Purity

    0.983

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Inhibitory Antibodies