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Molfinity

RAF265 - CAS 927880-90-8

RAF265 - CAS 927880-90-8

MF-0093009-01

$39.15 USD
$39.15 USD
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Product Details

  • Bioactivity

    RAF265 (CHIR-265) (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2.

  • Target

    VEGFR, Apoptosis, Raf, Autophagy

  • Related Pathways

    Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis, Autophagy, MAPK

  • CAS Number

    927782

  • Purity

    0.9956

  • Molecular Formula

    C24H16F6N6O

  • Molecular Weight

    518.41

  • SMILES

    Cn1c(Nc2ccc(cc2)C(F)(F)F)nc2cc(Oc3ccnc(c3)-c3ncc([nH]3)C(F)(F)F)ccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound