Ralimetinib - CAS 862505-00-8

Ralimetinib is a selective inhibitor that blocks phosphorylation of MK2 at Thr334, without affecting the phosphorylation of p38α MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc. Ralimetinib functions as an ATP-competitive inhibitor of p38 MAPK α/β, demonstrating IC50 values of 5.3 and 3.2 nM, respectively, and is under investigation as an anti-inflammatory and anticancer therapeutic.

Others, Autophagy, MAPK, p38 MAPK

Others, MAPK, Autophagy

862505-00-8

0.9921

C24H29FN6

420.53

FC=1C=CC(=CC1)C=2N=C(NC2C3=NC4=C(N=C(N)N4CC(C)(C)C)C=C3)C(C)(C)C

-20°C

Ice Packs

Small Compound