Raluridine - CAS 119644-22-3

Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM for the approved agents AZT, ddI (2',3'-dideoxyinosine), and ddC (2',3'-dideoxycytosine), respectively.

Others, Nucleoside Antimetabolite/Analog

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Others

119619

C9H10ClFN2O4

264.64

O=C1N([C@@H]2O[C@H](CO)[C@@H](F)C2)C=C(Cl)C(=O)N1

-20°C

Ice Packs

Small Compound