Ranbezolid - CAS 392659-38-0

Ranbezolid (RBx7644 free base) is an orally active oxazolidinone antibiotic effective against both Gram-positive and Gram-negative anaerobic bacteria, including Staphylococcus aureus, Staphylococcus epidermidis, and Bacteroides fragilis. It inhibits the 50s ribosomal subunit, with an IC50 value of 17 μM for bacterial ribosomes, and disrupts cell wall and lipid synthesis. Ranbezolid acts as a rapid bactericidal agent, significantly reducing bacterial load, and demonstrates improved cardiovascular safety. It is applicable in the study of antibiotics targeting anaerobic bacteria.

Antibiotic, Antibacterial

Microbiology/Virology

392621

C21H24FN5O6

461.44

O=C1N(C[C@H](CNC(C)=O)O1)C2=CC(F)=C(C=C2)N3CCN(CC=4OC(N(=O)=O)=CC4)CC3

-20°C

Ice Packs

Small Compound