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Ranirestat - CAS 147254-64-6
Ranirestat - CAS 147254-64-6
SKU:MF-0016929-01
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Product Details
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Bioactivity
Ranirestat (AS-3201) is an orally active and potent aldose reductase (AR) inhibitor with neuroprotective properties that ameliorates peripheral nerve dysfunction in rats with advanced diabetic polyneuropathy.Ranirestat inhibits the inflammatory response of high glucose-exposed endothelial cells and may be useful for the study of diabetic sensory-motor polyneuropathy.
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Target
Reductase
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Related Pathways
Metabolism, Endocrinology/Hormones
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CAS Number
147184
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Purity
>99.99%
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Molecular Formula
C17H11BrFN3O4
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Molecular Weight
420.19
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SMILES
Fc1cc(Br)ccc1CN1C(=O)c2cccn2[C@@]2(CC(=O)NC2=O)C1=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound