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Rebastinib - CAS 1020172-07-9

Rebastinib - CAS 1020172-07-9

MF-0018579-01

$32.42 USD
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Product Details

  • Bioactivity

    DCC-2036 (Rebastinib (DCC-2036) ) is a conformational control Bcr-Abl inhibitor for Abl1 (WT, IC50: 0.8 nM) and Abl1 (T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Rebastinib aimed at the Angiopoietin2-Tie2 pathway.

  • Target

    Apoptosis, FLT, Bcr-Abl, Src

  • Related Pathways

    Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling

  • CAS Number

    1020172-07-9

  • Purity

    0.9984

  • Molecular Formula

    C30H28FN7O3

  • Molecular Weight

    553.59

  • SMILES

    CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc4ncccc4c3)C(C)(C)C)c(F)c2)ccn1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound