Rebeccamycin - CAS 93908-02-2

Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.

ADC Cytotoxin, Antibiotic, Topoisomerase

Microbiology/Virology, DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related

93908-02-2

C27H21Cl2N3O7

570.38

O=C1C2=C3C(N(C=4C3=CC=CC4Cl)[C@@]5(O[C@H](CO)[C@@H](OC)[C@H](O)[C@H]5O)[H])=C6C(=C2C(=O)N1)C=7C(N6)=C(Cl)C=CC7

-20°C

Ice Packs

Natural Product