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Regorafénib N-oxyde (M2) - CAS 835621-11-9

Regorafénib N-oxyde (M2) - CAS 835621-11-9

MF-0004219-01

$37.66 USD
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Product Details

  • Bioactivity

    Regorafénib N-oxyde M2 is an active metabolite of Regorafenib, a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM) .

  • Target

    C-Kit, Drug Metabolite, PDGFR, VEGFR, c-RET, Raf

  • Related Pathways

    MAPK, Apoptosis, Tyrosine Kinase/Adaptors, Angiogenesis, Metabolism

  • CAS Number

    835601

  • Purity

    0.9948

  • Molecular Formula

    C21H15ClF4N4O4

  • Molecular Weight

    498.81

  • SMILES

    CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)cc[n+]1[O-]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound