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Regorafenib - CAS 755037-03-7

Regorafenib - CAS 755037-03-7

MF-0014037-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    Regorafenib (BAY 73-4506) is an orally active, multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ, exhibiting both antitumor and anti-angiogenic activity.

  • Target

    PDGFR, c-Kit, Tie-2, Raf, Autophagy, FGFR, VEGFR, c-RET

  • Related Pathways

    Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, MAPK, Autophagy

  • CAS Number

    755037-03-7

  • Purity

    0.9995

  • Molecular Formula

    C21H15ClF4N4O3

  • Molecular Weight

    482.82

  • SMILES

    CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound