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Molfinity

Rel-A-395 hydrochloride - CAS 2747996-65-0

Rel-A-395 hydrochloride - CAS 2747996-65-0

MF-0119008-01

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Product Details

  • Bioactivity

    Rel-A-395 hydrochloride is the relative configuration of A-395 hydrochloride. A-395 is an antagonist of protein-protein interactions within the polycomb repressive complex 2 (PRC2) . It inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 value of 18 nM.

  • Target

    Histone Methyltransferase

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    2747931

  • Molecular Formula

    C26H36ClFN4O2S

  • Molecular Weight

    523.11

  • SMILES

    FC1=C2C(CCC2=CC=C1)N3C[C@@H]([C@@H](N(C)C)C3)C4=CC=C(C=C4)N5CCN(S(C)(=O)=O)CC5.Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound