(rel) -Asperparaline A - CAS 195966-93-9

Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.2 Dietary administration of aspergillimide A (10 μg/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces T. colubriformis fecal egg count in gerbils.3

Others, AChR

Neuroscience, Others

195966-93-9

C20H29N3O3

359.47

[H][C@@]12C[C@]34[C@@H](C)CCN3C[C@@]1(C[C@]1(CC(=O)N(C)C1=O)C2(C)C)N(C)C4=O |TLB:20:1:8.9:23.25|

-20°C

Ice Packs

Natural Product