REM127 - CAS 1417823-67-6

REM127 is a small molecular compound that modulates cellular calcium homeostasis and provides neuroprotection. It efficiently restores the imbalance of calcium homeostasis in cell models caused by the pathological accumulation of tau protein. Furthermore, REM127 can effectively cross the blood-brain barrier and offers therapeutic benefits in animal models of Alzheimer's disease, particularly in ameliorating synaptic and cognitive deficits and slowing the progression of amyloid-beta and tau pathologies. This compound is utilized in the research of neurodegenerative diseases.

Calcium Channel, Beta Amyloid, Others

Neuroscience, Metabolism, Membrane transporter/Ion channel, Others

1417823-67-6

C20H20Cl2N4S

419.37

ClC=1C=CC(=CC1)C2=NSC(=N2)N3CCN(CCC=4C=CC=CC4Cl)CC3

-20°C

Ice Packs

Small Compound