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Remdesivir de (ethylbutyl 2-aminopropanoate) - CAS 2607871-93-0
Remdesivir de (ethylbutyl 2-aminopropanoate) - CAS 2607871-93-0
SKU:MF-0154763-01
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Product Details
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Bioactivity
Remdesivir de (ethylbutyl 2-aminopropanoate) is a recognized impurity in Remdesivir, a nucleoside analog demonstrating potent antiviral efficacy. It exhibits EC50 values of 74 nM against SARS-CoV and MERS-CoV in human airway epithelial (HAE) cells, and 30 nM against murine hepatitis virus in delayed brain tumor cells. Notably effective in vitro against SARS-CoV-2 (COVID-19) infection, Remdesivir has garnered attention for its application in controlling the spread of the virus, as supported by references [1] [2].
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Target
Others, Drug Metabolite
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Related Pathways
Others, Metabolism
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CAS Number
2607778
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Molecular Formula
C18H18N5O7P
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Molecular Weight
447.34
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SMILES
Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)Oc2ccccc2)[C@@H](O)[C@H]1O)C#N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound