Resibufogenin - CAS 465-39-4

1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current (I K) and transient potassium current (I A), it has pathological effects on central nervous system. 3. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction.4. Resibufogenina's major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5β-hydroxylation .

Others, NF-κB, Akt, GSK-3, PI3K, DNA/RNA Synthesis, CDK

Others, DNA Damage/DNA Repair, Stem Cells, Cytoskeletal Signaling, Cell Cycle/Checkpoint, NF-κB, PI3K/Akt/mTOR signaling

422

0.9917

C24H32O4

384.51

CC12CCC3C(CCC4CC(O)CCC34C)C11OC1CC2c1ccc(=O)oc1

-20°C

Ice Packs

Natural Product