Resolvin D4 - CAS 1025684-60-9

Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid . [1] It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.[2][3] RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection. [3] With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.[3] It also promotes the clearance of apoptotic neutrophils by human fibroblasts.[3]

Others, Antibacterial

Microbiology/Virology, Others

1025615

C22H32O5

376.493

CC\C=C/C[C@H](O)\C=C/C=C/C\C=C\C=C\C=C\C(O)[C@@H](O)CCC(O)=O

-20°C

Ice Packs

Small Compound