RET-IN-19 - CAS 2484919-71-1

RET-IN-19 is a potent inhibitor of RET and exhibits anticancer effects on RET-wt (IC50: 6.8 nM) and RET V804M (IC50: 13.51 nM) .RET-IN-19 can be used to study non-small cell lung cancer (NSCLC) .

Others, c-RET, Aurora Kinase, c-Fms, MAPK, EGFR

Chromatin/Epigenetic, Apoptosis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Others, MAPK, Angiogenesis, Cell Cycle/Checkpoint

2484847

C28H28N6O4S

544.62

N(C1=C2C(NC(=C2)C3=CC=C(S(C)(=O)=O)C=C3)=NC=N1)C4=CC=C(CC(NC=5C=C(C(C)(C)C)ON5)=O)C=C4

-20°C

Ice Packs

Small Compound