RET-IN-25 - CAS 2965703-02-8

RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor effective against medullary thyroid carcinoma (MTC), with half-maximal inhibitory concentrations (IC50s) of 3.6 μM at 3 days and 3.0 μM at 6 days in TT (C634R) MTC [1].

C-RET, Others

Apoptosis, Tyrosine Kinase/Adaptors, Others

2965703-02-8

C22H17N3O5S

435.45

O=[N+](C1=CC=C(N=C2)C(C3=C2C(NC(C4=CC=C(C=C4)C)=O)=C(C(OCC)=O)S3)=C1)[O-]

-20°C

Ice Packs

Small Compound