Rezatapopt - CAS 2636846-41-6

Rezatapopt (PC14586) is a small molecule p53 reactivator with anti-tumor activity that selectively binds to the cleft present in the TP53 Y220C mutant protein and restores the p53 wild-type (normal) conformation and transcriptional activity, and can be used to study locally advanced or metastatic solid tumors.

Others, MDM-2/p53, p53

Others, Apoptosis

2636846-41-6

0.9812

C28H31F4N5O2

545.57

N(C1=C2C(N(CC(F)(F)F)C(C#CCNC3=C(OC)C=C(C(NC)=O)C=C3)=C2)=CC=C1)[C@H]4[C@@H](F)CN(C)CC4

-20°C

Ice Packs

Small Compound