RGH-122 - CAS 2355304-05-9

RGH-122 (compound 43), characterized as an orally active, potent, and selective hV1a receptor antagonist, demonstrates significant affinity with a K i value of 0.3 nM and an IC 50 of 0.9 nM. It exhibits microsomal stability, indicated by a CL int value of 13/28/25 μL/min/mg [1].

Vasopressin Receptor

GPCR/G Protein

2355304-05-9

C24H25ClN4O3

452.93

ClC=1C=C2CC3(CC=4N(C2=CC1)C(=NN4)[C@@H]5CC[C@@H](OC6=CC=CC=N6)CC5)OCCO3

-20°C

Ice Packs

Small Compound