Rhapontigenin - CAS 500-65-2

Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM) .

Antibacterial, Cytochromes P450, Antifungal

Microbiology/Virology, Metabolism

433

0.9988

C15H14O4

258.27

COc1ccc(\C=C\c2cc(O)cc(O)c2)cc1O

-20°C

Ice Packs

Natural Product