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Rho GTPase inhibitor 1 - CAS 1309252-99-0

Rho GTPase inhibitor 1 - CAS 1309252-99-0

MF-0115088-01

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Product Details

  • Bioactivity

    Rho GTPase inhibitor 1 (compound 7) is a potent inhibitor of Rho GTPase. It exhibits high affinity for Cdc42, Rac1, and RhoA, with dissociation constants (KDs) of 151 μM, 352 μM, and 232 μM, respectively. Additionally, Rho GTPase inhibitor 1 reduces cell migration in glioblastoma cell lines.

  • Target

    Ras

  • Related Pathways

    GPCR/G Protein, MAPK

  • CAS Number

    1309153

  • Molecular Formula

    C18H16N2O

  • Molecular Weight

    276.33

  • SMILES

    N1=CC=2C=CC=CC2C(=C1)C3=CC=CC4=C3OC(CN)C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound