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Rho-Kinase-IN-2 - CAS 2573071-18-6

Rho-Kinase-IN-2 - CAS 2573071-18-6

SKU:MF-0050680-01

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  • Bioactivity

    Rho-Kinase-IN-2 (Compound 23) is an orally active and selective inhibitor of Rho Kinase (ROCK) with CNS penetration, exhibiting a high affinity for ROCK2 with an IC50 of 3 nM. This compound is of potential interest for further investigations in Huntington's disease research [1].

  • Target

    Others, ROCK

  • Related Pathways

    Others, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Stem Cells

  • CAS Number

    2573047

  • Molecular Formula

    C20H25FN4O2

  • Molecular Weight

    372.44

  • SMILES

    FC=1C(N2C[C@@H](C)N(C(N[C@H](C)C3=CC(OC)=CC=C3)=O)CC2)=CC=NC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound