Rhosin - CAS 1173671-63-0

Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM) . Rhosin does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin causes cell apoptosis.

Apoptosis, Rho, Ras

GPCR/G Protein, Apoptosis, Cell Cycle/Checkpoint, MAPK

1173608

C20H18N6O

358.4

C([C@H](C(N/N=C/C1=CC2=C(C=C1)N=CC=N2)=O)N)C=3C=4C(NC3)=CC=CC4

-20°C

Ice Packs

Small Compound