Ribociclib hydrochloride - CAS 1211443-80-9

Ribociclib hydrochloride (LEE011 HCl) is a selective, orally active cyclin-dependent kinase CDK4/6 inhibitor (IC50=10/39 nM) that blocks cell cycle progression and inhibits tumor cell proliferation.

Cell Cycle Arrest, CDK

Cell Cycle/Checkpoint

1211354

0.9987

C23H31ClN8O

471

Cl.O=C(C1=CC=2C=NC(=NC2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5)N(C)C

-20°C

Ice Packs

Small Compound